There's a new, minor bug in the current release of MCFX Basic - I assume it's also in the Pro version.
If a study is set to "User Defined" scaling and one of the limits is zero, the scaling will not save correctly. When the workspace is closed and reopened, the scaling limits default to +1 and -1.
The workaround solution is to select a user defined limit close to zero, but non-zero.
For example, if I apply an RSI study to a price pair, and set a "User Defined" scale range of 0 to 100, when I save, close, and reopen the workspace, the scale range limits have been reset to -1 and +1. If, on the other hand, I set a range of 1 to 100, the scaling is saved and restored correctly.